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On this reddit thread some solutions like using SIP gateway with echo cancellation were discussed. http://www.reddit.com/r/nexus4/comments/15ip1v/is_voip_just_

• xur17 14y ago
  The problem is that: 1) Software echo cancellation doesn't work as well as hardware echo cancellation. 2) The phone uses a second microphone to cancel out background noise during calls. This isn't used for any voip calls. I'm told it is extremely loud when a car drives by, and a little bit of wind make it sound like I'm in a hurricane. Is there some hardware reason they can't open up access to this chip? Does audio for calls get routed directly to the gsm chip, so we don't have access or something?