It makes sense to support IE 6 when you sell a product to an enterprise, the UI is task oriented and doesn't have to be pixel perfect to entice users. The tric

It makes sense to support IE 6 when you sell a product to an enterprise, the UI is task oriented and doesn't have to be pixel perfect to entice users. The trick is to make supporting IE 6 cost effective. You can still use semantic markup and CSS layout, it would just be a simplified version of what you serve modern browsers. It's called graceful degradation, and with a well defined templating system, it's feasible without laborious adjustments and hacks. Some enterprises really can't upgrade, and if you are willing to support that one troublesome browser, you can still sell the product behind it, which can be innovative and useful.