Hurts? Immediate release methylphenidate has a half-life of 2-4 hours, while Concerta has a duration of effect of 12 hours. Given the narrow therapeutic window

Hurts? Immediate release methylphenidate has a half-life of 2-4 hours, while Concerta has a duration of effect of 12 hours. Given the narrow therapeutic window of methylphenidate and the harsh wthdrawal syndrome, they are different drugs.