3 ms·
To put this in perspective, Novartis Glivec is the beta crystalline form of 'imatinib mesylate' - an already known compound which went out of patent. Novartis f
by anuraj 14y ago
To put this in perspective, Novartis Glivec is the beta crystalline form of 'imatinib mesylate' - an already known compound which went out of patent. Novartis failed to establish that the new form has demonstrable efficacy over non-crystalline form. As per section 3 (d) of Indian Patent Law designed to prevent Evergreening - inventions that are mere "discovery" of a "new form" of a "known substance" and do not result in increased efficacy of that substance are not patentable. Indian patent law follows guidelines set forth by WTO under TRIPS agreement. So Novartis has exhausted all their legal defences. Novartis did not get even one favourable verdict in the entire legal battle which played out in 3 different courts of law.
- jostmey 14y agoWould the crystalline form even be a viable drug? Don't drugs have to be soluble in order to circulate in the blood stream? Is the beta cystalline form the same chemical formula as the soluble form?
- anuraj 14y agoBeta crystalline form has the same chemical formula as the non-crystalline form and is soluble.