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There's a super-fundamental discovery about ageing--and a possible "cure" to ageing--that longevity researchers seem to be WAY TOO cautious in discussing and pu
by cantrevealname 14y ago
There's a super-fundamental discovery about ageing--and a possible "cure" to ageing--that longevity researchers seem to be WAY TOO cautious in discussing and pursuing.
These are telomeres.
Telomeres are a DNA pattern that sets a hard limit on the number of times a cell will divide (and thus repair itself). When the limit is reached, cells stop dividing (then accumulate damage and age). The limit for humans is something like 70 cellular divisions if I remember right.
If you can find a way to lengthen or reset telomeres, you'd have cellular immortality.
The first time I heard about it ten years ago, it blew my mind. To me, this is the biologist's equivalent of a proof that P=NP would be to a computer scientist. I expected enormous interest and research into this, and billions of dollars poured into it, but I'm amazed that it hasn't happened and most people still have never heard of telomeres.
Why isn't there an Apollo-mission-let's-devote-the-resources-of-the-whole-country effort into this? I think it comes down to fear of researching or financing anything with the word "immortality" in it. You'd sound like a crackpot even though the science is sound.
A brief intro on telomeres:
http://www.news-medical.net/health/Telomere-What-are-Telomeres.aspx http://www.news-medical.net/health/Telomere-What-are-Telomer...
- melling 14y agoReally? I think it has been in the press for a couple of decades now. At any rate, it's probably wise to spread the research money around. The war on cancer started with Nixon is about 40 years old, and we still have a long way to go? My hope is that crowd sourcing and funding really catches for science on in the next few years. Wouldn't it be great to have a lot more resources, both money and people, working on interesting science problems?
- aneth4 14y agoTelomeres exist to prevent out of control cell reproduction, ie cancer. Turn them off and you get a very high cancer rate. That's not to say we can't end aging by extending them, but it's not that simple.
- stcredzero 14y ago> Turn them off and you get a very high cancer rate. Or rather, enable telomere repair mechanisms, and you get a higher cancer rate. One of the things cancers must do in order to keep existing is to activate teleomerase or the alt telomere repair mechanism.
- JulianMorrison 14y agoTelomeres are not immortality. They are "ulimit" for cells. Maximum number of forked processes. Set the limit to unlimited, oops cancer. Also, they are only one of the factors that combine to cause of ageing.