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"Although macrophages also attacked blood cells expressing CD47 when mice were given the antibody, the researchers found that the decrease in blood cells was sh
by wwwtyro 14y ago
"Although macrophages also attacked blood cells expressing CD47 when mice were given the antibody, the researchers found that the decrease in blood cells was short-lived; the animals turned up production of new blood cells to replace those they lost from the treatment"
That's great -- does anyone know if any other cells in the body express CD47? Especially ones that can't be replaced so easily?
- viraptor 14y agoNo specific answer from me, but I guess digging through some top entries from pubmed can answer that. http://www.ncbi.nlm.nih.gov/gene?term=%28cd47[gene]%29%20AND%20%28Homo%20sapiens[orgn]%29%20AND%20alive[prop]%20NOT%20newentry[gene]&sort=weight http://www.ncbi.nlm.nih.gov/gene?term=%28cd47[gene]%29%20AND... may be a good start.