This is what Twitter's Lists functionality is for. I have separate lists of people for topics I am interested in, such as running, android, infosec, etc. The do

This is what Twitter's Lists functionality is for. I have separate lists of people for topics I am interested in, such as running, android, infosec, etc. The downside is that people on your lists don't enjoy the same capabilities as the people you follow, so they can't DM and they might be insulted that you show as not following them.