3 ms·
Clearly? Identical twins do not have the same likeliness of developing T1DM. Genetics do not explain why we have had a significant global growth (~3% per year
by strebler 14y ago
Clearly? Identical twins do not have the same likeliness of developing T1DM. Genetics do not explain why we have had a significant global growth (~3% per year) in the number of cases of Type 1 Diabetes Melanoma (T1DM) in recent decades. There are even a number of vaccines in development (with early successes).
In many cases a T1DM diagnosed child was sick with a cold/flu immediately prior to onset of T1DM. Disease has been theorized for quite a long time to influence the immune system's reaction. A large majority of T1DM cases are diagnosed in winter, Vitamin D / sunlight has been hypothesized to play a role - more northern countries tend to have higher rates.
Even in the hereditary factor, here is research indicating that epigenetics play a role - timing of food shortages during our grandparents' lives significantly increases likeliness of T1DM. That appears to be an environmental factor tweaking our genes.