I agree that 10,000 years is sufficient time for evolution to affect the human genome. But the "diseases of civilization" that paleo worries about (cancer, hea

I agree that 10,000 years is sufficient time for evolution to affect the human genome. But the "diseases of civilization" that paleo worries about (cancer, heart disease, type 2 diabetes, etc) tend to kick in at 50+, don't they? So it seems like evolution's ability to influence those would be limited, at best.