Check out Dr.Sulzer's research. A lot of these studies are very hard to understand without some organic chem and biochem background. Reading the abstract is si

Check out Dr.Sulzer's research. A lot of these studies are very hard to understand without some organic chem and biochem background. Reading the abstract is simply not enough feel the significance of these research. The other problem is access to these articles through journal subscription is quite expensive. I always figure that methamphetamine does some long-term damage, but when they found melanin accumulation in the neurons by examining brain slices, it was pretty alarming. The mechanism of action between amphetamine and methamphetamine is too similar to rule out the possibility of long-term damage. It just doesn't make sense to take adderall when dexmethylphenidate (focalin) gives most of the benefit without ritalin's side effects. In the long-term, I'm still quite leery of dexmethylphenidate, particularly how it acts as a releaser at high concentration. I haven't come across any papers that describe its mechanism of action as a releasing agent. This is another reason why I only use it to study and practice piano. As long as you're learning, it's easy to justify that the benefit outweigh the cost.