Very interesting talk Leads me to wonder - has anyone done a study of any large-scale program to check where the slow spots are? It's not that I don't trust th

Very interesting talk Leads me to wonder - has anyone done a study of any large-scale program to check where the slow spots are? It's not that I don't trust the speaker, he makes excellent points and is obviously a great memeber of the community. But it would be very interesting if he were able to say: "Using PyPy's secret 'hint' API, only in drop-dead obvious places, improved performance by a factor of 5".