I really like RequireJS. The have a build optimizer. It is pretty handy. I have not tried LabJS. It looks pretty interesting. I am looking forward to more

I really like RequireJS. The have a build optimizer. It is pretty handy. I have not tried LabJS. It looks pretty interesting. I am looking forward to more about KnockoutJS. It seems like it would really reduce the amount of code you need to write compared to pure JQuery.