7 ms·
It amazes me that this article still pushes the agenda that "fat makes us fat." If there's one thing that hasn't proven out at all, it's that fat makes us fat!
by Goladus 14y ago
It amazes me that this article still pushes the agenda that "fat makes us fat." If there's one thing that hasn't proven out at all, it's that fat makes us fat!
Overeating makes us fat. Caloric surplus makes us fat. It's pretty trivial to consume a caloric surplus eating lots of fatty foods. In that sense: fat makes us fat and it's silly to try denying it. It doesn't mean a low-fat diet will make you lose weight, it just means that high-fat diets are going to make you fat.
Excellent refutation of Taubes hypothesis:
http://wholehealthsource.blogspot.com/2011/08/carbohydrate-hypothesis-of-obesity.html http://wholehealthsource.blogspot.com/2011/08/carbohydrate-h...
Insulin does not regulate fat storage, leptin does. Obesity is a complex state and there are no simple answers. A diet that may be best for weight loss in one individual may not be the same diet that is best for another. This seems particularly likely if one of the two individuals is not obese.
The problem with "low-fat" processed food in particular is that the fat is often replaced with sugar to add taste, but sugars and other high-carb grains are more problematic than fat consumption.
They aren't more problematic. Aside from the relationship to cholesterol levels, they are the same problem.
The problems are:
1. High caloric density.
2. *Vanishing* caloric density-- foods that prevent satiation.
3. Addictive flavors and sensations that cause cravings.
Calorie surplus makes you gain weight, and unless you're building muscle it's going to be fat. All Ludwig's experiments suggest (as reported by Taubes, with lazy citation[1]) is that obese people who have just lost 10-15% of their weight tend to have a higher daily metabolism without conscious addition of physical exercise on a low-carb diet, compared to a low-fat diet or a low-GI diet. This in turn suggests it might be easier to maintain calorie balance on a low-carb diet than a low-fat diet (for formerly obese people who have just dieted to lose 10-15% of their body weight).
postcript:
I would also add that lifestyle changes are a factor as well as diet. Addictive foods are more dangerous to someone who has a snacking/forager mentality than someone who plans and eats fixed meals every day.
[1] This appears to be the study referenced in the NY Times article: http://jama.jamanetwork.com/article.aspx?articleid=1199154 http://jama.jamanetwork.com/article.aspx?articleid=1199154
- schoper 14y agoI'm not too impressed by Stephan Guyenet's article. He is wrong about one of his main points that fat is completely regulated by the brain and that insulin does not cause fat gain. You can Google for photographs of people who have done insulin injections in a single place over many years (rather than moving the injection point around) and see huge fat deposits at the injection site. That has got to be tissue regulation. Further, lipodystrophy is hard to explain by only invoking brain regulation. We know that artificial insulin is a great way to gain weight. But is that only for diabetics? Hardly. It works just as well on athletes. Stop by your local gym and ask any of the chemically-assisted bodybuilders there for details. Insulin injections are a very common way to put on weight while bulking. The idea that the body is "confused" by food density, which seems to underlie many of your ideas, is simply unsupported. The brain is very good at measuring calorie intake irrespective of density. I could point you to rat studies to confirm this, but I'd rather propose the following experiment that you can try in your own kitchen: Try making cream of cauliflower soup tonight, one with skim milk and the other with heavy cream. Measure how many spoonfuls of each that you can eat before getting full. Your brain does not get fooled by food density.
- nicholas73 14y agoI don't see how your example is related. Firstly, Stephan's description of the brain's role is that it regulates both appetite and metabolism. These mechanisms indirectly regulate fat storage. Insulin of course would cause fat storage, but your example neither eliminates the other mechanisms, nor is a fault in the brain signalling system as it's an local injection. It's unrealistic to expect the system to have such a fine degree of control. The role of insulin is to remove excess energy and funnel it into fat cells. That is of course why you see the weight gain. But that is only one part of the system. As for your experiment, I can say it won't work on me - I typically eat until there is no food left, regardless of "fullness". In fact if I were at a buffet I would eat to actual physical fullness. Yet I do not have discomfort and I am still lean enough for me stomach muscles to show. I have stayed the same weight for the last 15 years. Thus, there has to be a regulation system, perhaps as proposed by Stephan.
- jcfowler 14y agoGuyenet literally addresses the issue of fat gain around injection sites in the linked article. Like you, I am generally not impressed with articles I have not read.
- schoper 14y agoHe addresses it (barely), but not in regards to brain versus tissue regulation, which is the context where I brought it up. What he says (the injection site issue is "argument #4" in his article): "cases where insulin levels and/or insulin sensitivity are changing independently of one another, [...] through drugs. This is why they're irrelevant..."
- Goladus 14y agoTry making cream of cauliflower soup tonight, one with skim milk and the other with heavy cream. Measure how many spoonfuls of each that you can eat before getting full. The important question is not how many spoonfulls it's, how many calories? 1 cup of skim milk is 86 calories. 1 cup of heavy cream is 821 calories. Let's imagine something a little more simple than cauliflower soup: strawberries and cream. 50 calories of strawberries + 1/2 cup of heavy cream would be 460 calories. An easy, common dessert. You could also eat those 50 calories of strawberries along with 5 cups of skim milk. Or maybe eat a whole pound of strawberries (150 calories) and only need 3.6 cups of skim milk. Or maybe 50 cals of strawberries, 100 calories of shortcake, and 3.6 cups of skim milk. Which eater is more likely to overshoot their ideal caloric intake by a bit? Which eater is more likely to stop eating the moment they get full? The brain isn't fooled, but it doesn't have to be. The person who gorged on the shortcake knows they overate, but they still took on more calories than they're going to burn. And of course-- if the brain can be fooled, being fooled by high-calorie foods is going to be worse than being fooled by low-calorie foods, on average. Which is more likely to result in a calorie surplus: Salt on your mashed potatoes or salt on your buttered, cheese-smothered mashed potatoes? That is why I listed calorie-dense foods as #1. Without understanding caloric density, it's very hard for anyone to know (without outside guidance) when or how they are being fooled.
- scythe 14y agoThere are two things that come to mind when we ask if dietary fat causes obesity. First: fat and carbohydrates sum to literally all of food. The caloric value of protein is (essentially) negligible. What is certainly the case is that we can point to people who are fat (preferred term) on a low-fat diet. We can point to people who are fat on a fat-intermediate diet (rough balance of fat/carbs). Can we find many people who are fat on a low-carb diet? I suggest that if we do, most such people will not be found eating fat in its natural form, but as rendered fat and pressed oil. It is almost certainly the case that the way in which fat is consumed affects satiety: the body cannot see a caloric benefit from fat until it is beta-oxidized in the liver, many hours after it is consumed. So in order to estimate how much you have eaten, the body assumes you have consumed fats in their natural form. This is key to most low-carb diets: fat is usually consumed in its natural form, since nobody drinks oil (eww) and fatty snacks such as potato chips are banned. It is also an intrinsic feature of the "paleo" diets, which ban processed foods. So, it might not be too much of a stretch to say that fat as a naturally occuring part of foods like almonds does not make us fat. The second thing that comes to mind is the balance of omega-6 and omega-3 fatty acids in a healthy diet. When this is tilted excessively in favor of omega-6, the body produces an excess of certain endocannabinoids (arachidonic acid) which contribute to overeating: http://www.sciencedaily.com/releases/2010/07/100726221737.htm http://www.sciencedaily.com/releases/2010/07/100726221737.ht... [NB: the mechanism is up in the air. The effect is real.] The additional, final consideration is the alleged link (as stated in the article) between consumption of land meats and obesity. See https://en.wikipedia.org/wiki/Red_meat#Obesity https://en.wikipedia.org/wiki/Red_meat#Obesity I've been harping on "natural", and meat is natural, so what gives? Weirder yet, the correlation is with meat protein, not with fats. And we do know, though, that people on e.g. ketogenic diets lose weight while eating lots of meat: http://ajcn.nutrition.org/content/82/1/1.short http://ajcn.nutrition.org/content/82/1/1.short The simplest way to assign blame is to cry confounding: while meat itself is natural, it is rarely consumed in a natural-food context. Instead, since meat is culturally considered unhealthy, it is often eaten on white bread or in a pack of Lunchables. Support for the confounding hypothesis would be a low r-value in studies that link meat consumption to body fat (i.e. total variation in body fat is only weakly related to variation in meat consumption); falsification might be a very high r-value, or a very well-controlled study. [NB: I believe the confounding hypothesis.]
- shanev 14y agoThe truth is, you guys are both right. The only people I know who think obesity is complex are the people who still believe in calories in = calories out. Calories DO matter, but only at a certain point. Fat only makes you fat if you are also consuming a huge amount of calories. But in that case, anything can make you fat, including carbs and protein. If you stick to a paleo/primal diet, it's very hard to get fat because we feel satiated since leptin is being properly regulated. You can also lose weight with caloric restriction, but if your diet consists of pizza and other gluten-containing foods, you will constantly struggle with it due to the addictive nature of these foods. You'll probably be skinny fat (skinny everywhere yet have visceral around your waist). And you won't be precluded from getting diabetes or another disease of civilization. Like anything, the devil is in the details and the truth is in the middle. But this stuff is not a mystery. Industrial food producers want health to be a mystery for us, so they can sell us their junk. It's actually very simple. Stick to foods that can be obtained by hunting or foraging, and don't eat anything that comes out of a package. My dad followed this advice for a year after getting heart surgery. He went from being pre-diabetic to having normal biomarkers. His doctors are amazed. I'm glad I didn't let him follow their advice of loading up on statins and drinking Ensure shakes.
- Goladus 14y agoThe only people I know who think obesity is complex Do you think obesity is not complex? You'll probably be skinny fat Probably? What if you are not? Do you just not count those people?
- shanev 14y agoLet me clear that up. The biochemistry of obesity is not trivial, but knowing what to eat to control your weight is not hard. It just takes some research and self experimentation. It's empowering when you figure out how certain foods affect you. I'm at a point where if I want a six pack again, I know exactly what to eat and for how long. I understand the makeup of most of the foods I eat and understand the consequences of eating them, how they will affect my blood sugar, which ones trigger my asthma and eczema, etc. When you throw out all the bullshit spewed out by mainstream health media, and take human anthropology into account, it is amazing how quickly you realize how much we've been duped into thinking it's all about calories. If you're on a Standard American Diet and don't get fat (or skinny fat), you'll most likely get some other disease caused by inflammation, like cancer, Parkinson's, or Alzheimer's. There are always exceptions though, like genetic outliers, people who produce high amounts of salivary amylase, and high level athletes who burn through all that sugar.
- fingerprinter 14y ago> Insulin does not regulate fat storage, leptin does. Obesity is a complex state and there are no simple answers. A diet that may be best for weight loss in one individual may not be the same diet that is best for another. This seems particularly likely if one of the two individuals is not obese. You have this backwards. Insulin DOES help regulate fat storage (among other things). Leptin controls appetite and can act as an indication of overall adipose levels. It is conjectured that treating things like diabetes with both insulin and leptin together is better than insulin alone. http://en.wikipedia.org/wiki/Leptin http://en.wikipedia.org/wiki/Leptin and http://en.wikipedia.org/wiki/Insulin http://en.wikipedia.org/wiki/Insulin And I'll jump in on this calories vs everything else. If, as I've said many times before in other posts, all you care about is weight, only track calories (you'll most likely end up skinny-fat...but at a certain weight. Horray! You are now unhealthy at a lower weight. Congratulations!) If you care about losing fat, track macros and reduce carb intake to lose fat (along with weight lifting, HIIT and some carb-refeeds to manage hormone levels). This is a rather complex topic, though I'm going to try and frame it a different way. What is the most effective way to put on lean, pure muscle mass? Weight lifting? A caloric surplus? High protein? Yeah, sure, all of that. Do you know what is even more effective? Steroids, specifically some combination of test, deca (or dbol), maybe some sustanon. What is the most effective way to lose body fat, particularly get to a ridiciously low level of body fat (think, getting on stage in a thong)? Caloric deficit? Low-carb? HIIT? hours of cardio? How about steroids again. Clen+Tren+Test. Sure, in both cases, caloric excess or deficit will help, but the stacks ALONE will work. Why does that matter? Everyone always overlooks the hormones. Why would it be any different if we don't talk about steroids? Hormones play a very important role in putting on muscle (think, stimulate the muscles by weight lifting, give them aminos (protein) to rebuild and spike insulin to make sure the muscles get the protein). And losing fat is no different (keeping fat high is vital to keeping testosterone high, protein to spare the muscles and lowerish carb to make the body look for an energy source (ie. fat) that you aren't providing. Throw in some weight training and HIIT to further deplete your glycogen stores. Viola, fat loss, muscle spared. Carb refeed once a week to reset your hormones (don't go into starvation mode) and you have a wash-rince-repeat cycle). So, yes, calories matter, but only once you understand the broader picture. If you only talked calories, frankly, you can't be taken seriously.
- 14y ago
- frooxie 14y agoTaubes has responded to the wholehealthsource critique (I have not read it, but it was referred to as a "thorough multi-part smack down"): http://garytaubes.com/2011/09/catching-up-on-lost-time-ancestral-health-symposium-food-reward-palatability-insulin-signaling-carbohydrates-kettles-pots-other-odds-ends-part-i/ http://garytaubes.com/2011/09/catching-up-on-lost-time-ances...
- Goladus 14y agoI'll read it, but I'm unfortunately suspicious now. When a response to a piece as thorough and logical as Guyenet's gets called a "smack down," it's almost always full of rhetorical blustering which is highly satisfying to people predisposed to side with the smacker. But anyone with genuine interest in seeing the discussion advance and see where Guyenet's argument breaks down is likely to be disappointed. Beginning the article with a lengthy, seemingly unrelated narrative (shaggy dog story) is precisely the sort of rhetorical distraction that I am disappointed to see.