Zencart was/is the leader, Magento is the newcomer but looks very strong. Wordpress has very good shopping cart plugins in case you want to add a publisihing &

Zencart was/is the leader, Magento is the newcomer but looks very strong. Wordpress has very good shopping cart plugins in case you want to add a publisihing & advertising platform to your shop. (highly recommended!) Also Shopify can be a solution.