If you are interested in this question, I recommend listening to the following recording of a talk given by Alicia Danforth, research assistant to Dr. Charles G

If you are interested in this question, I recommend listening to the following recording of a talk given by Alicia Danforth, research assistant to Dr. Charles Grob (who ran the psilocybin research study mentioned in this article).[1] She goes in to quite a lot of detail as to exactly how they conducted their study, and what measures they took to help prevent bad trips. As supplementary reading, see the Erowid page on Dr. Charles Grob,[2] a book called The Secret Chief Revealed by Myron J. Stolaroff (about a famous psychedelic therapist),[3] and The Psychedelic Experience FAQ.[4] The book and FAQ have lots of great suggestions for having positive, constructive trips. One of the key things you can do to increase the odds of having a good trip is having a trusted, experienced guide or sitter. To that end, I recommend the following sitter guidelines: [5][6][7][8] [1] - http://www.matrixmasters.net/archive/Playalogues/131-Danforth2007Playalogue.mp3 http://www.matrixmasters.net/archive/Playalogues/131-Danfort... [2] - https://www.erowid.org/culture/characters/grob_charles/grob_charles.shtml https://www.erowid.org/culture/characters/grob_charles/grob_... [3] - http://www.amazon.com/Secret-Chief-Revealed-Myron-Stolaroff/dp/0966001966/ http://www.amazon.com/Secret-Chief-Revealed-Myron-Stolaroff/... [4] - https://www.erowid.org/psychoactives/faqs/psychedelic_experience_faq.shtml https://www.erowid.org/psychoactives/faqs/psychedelic_experi... [5] - http://csp.org/nicholas/A59.html http://csp.org/nicholas/A59.html [6] - https://www.erowid.org/psychoactives/guides/guides_article2.shtml https://www.erowid.org/psychoactives/guides/guides_article2.... [7] - http://www.maps.org/gateway/%5B55%5D181-197.html http://www.maps.org/gateway/%5B55%5D181-197.html [8] - http://www.maps.org/news-letters/v09n1/09124mar.html http://www.maps.org/news-letters/v09n1/09124mar.html