"I tend to think of these things as karmic accelerators. The karma that would usually ripen over 2 years is, instead, experienced in 12 hours." That might play

"I tend to think of these things as karmic accelerators. The karma that would usually ripen over 2 years is, instead, experienced in 12 hours." That might play a role (assuming there is such a thing as karma). However, I think there's a lot more to it. Psychedelics can be used constructively or destructively, therapeutically, religiously, or recreationally. They can be used with positive intention, negative intention, or no particular intention. They can be used in a safe, pleasant setting, in indifferent settings, or in a scary, unpleasant setting. You could use them alone or with friends, strangers, with wise, knowledgable, trusted guides, or in a mix of any of the above. The person using them may not know what to expect, or might be well educated on the effects of psychedelics. The person might be very experienced or this might be their first trip. The dose of the substance might be small or large. The substance may be pure or impure. The person might fight against the effects of the substance or give in. They may have great respect for the substance or have a very casual or cavalier attitude towards it. All of these factors and more can greatly affect what happens during the experience. To reduce it all to karma or any other single factor is way too simplistic.