The main problem with psyco is lack of 64-bit support. While a new psyco would be nice, what really would make sense is a boost-like tophat on rpython so you c

The main problem with psyco is lack of 64-bit support. While a new psyco would be nice, what really would make sense is a boost-like tophat on rpython so you can drop into it and compile your performance-critical routines. Today people do that with C++ and boost. Cython/pyrex don't cut it because they don't allow you to create C-style strongly typed objects with Python-accessible methods. Maybe you can do that today, but good luck finding out by reading the pypy docs.