My guess is yes. Twitter is a new protocol, and in the past new protocols have always generated new companies. The one catch here is that this protocol is con

My guess is yes. Twitter is a new protocol, and in the past new protocols have always generated new companies. The one catch here is that this protocol is controlled by a private company. So you'd have to worry about the possibility that if you did something successful, they'd try to take it over themselves. I think one could probably protect oneself, though, by doing something that's enabled by Twitter, but very far removed from the kind of thing the Twitter guys understand. E.g. don't try to do search for Twitter, because Twitter will probably own that. But if you did something combining, say, Twitter and real estate, they'd probably steer clear of it.