Not playing in the conspiracy here, but the lack of transparency is concerning. I know the weight and complexity of the process of designing a clinical study, a

Not playing in the conspiracy here, but the lack of transparency is concerning. I know the weight and complexity of the process of designing a clinical study, and I don't doubt that, in most cases, the placebos are well crafted. However, I'm sure that, in some cases there are oversights in the placebo choice (we do make mistakes), and we don't know which ones. There are also big financial stakes, and pharmaceutic firms are known to cheat while attempting to bring drugs to the market. The burial of negative studies come to mind.