Well, I think the trick is the find meaning in small things and not to worry too much (all of the time) about how what you do fits in the grand scheme of things

Well, I think the trick is the find meaning in small things and not to worry too much (all of the time) about how what you do fits in the grand scheme of things. Because, indeed, things that are meaningful on a small scale might be absurd when you put them in a bigger context. So I don't see a contradiction here. Of course worrying about what things mean on a larger scale can be virtuous, but you also want to come to terms with your limitations as a human being in a specific context.