I, too, have run through several of these apps. I'll continue -- axure, keynote, indesign, and others. All with the same problems described. I've finally arriv

I, too, have run through several of these apps. I'll continue -- axure, keynote, indesign, and others. All with the same problems described. I've finally arrived at pencil, paper, and a basic PHP,Smarty,Bootstrap/Zurb,backbone framework that lets me create a bunch of components, pages, and anything else I need. It works for me because I can sit down and start making pages that link to one another. Then, once it feels right I can start back-filling with database stuff, backbone api calls, and all that. But in the end I just ended up making another framework, albeit one that is closely tied to the frameworks above. I think of it as my own drupal, but one with less bloat :-)