I would highly recommend looking at Titanium over PhoneGap. Titanium provides an API to actual native elements, while PhoneGap simply creates a UIWebView wrappe

I would highly recommend looking at Titanium over PhoneGap. Titanium provides an API to actual native elements, while PhoneGap simply creates a UIWebView wrapper around your code. Nothing beats real Obj-C code, but Titanium comes pretty darn close. From what I hear, Monotouch is another good one, but it sounds like you're already more familiar with JS.