The problem with the entire argument that you're making is that the natural rate of remission in uncomplicated major depressive episodes is very close to the ra

The problem with the entire argument that you're making is that the natural rate of remission in uncomplicated major depressive episodes is very close to the rate that SSRIs create, individually, and very close in terms of timing. If you do something more like STAR-D you see higher rates, but that also takes so long that many people naturally remit.