Not self-approval, but maybe look at the clinical trial reforms in China (2016). There seems to be a lesson there to learn from. They made the trial system a lo

Not self-approval, but maybe look at the clinical trial reforms in China (2016). There seems to be a lesson there to learn from. They made the trial system a lot more flexible, and China has recently overtaken the US in the # of new drugs patented, about a third worldwide. That number was ~ zero mere ten years ago.