While AlphaFold is great, to my knowledge, these proteins have several non-significant IDRs (intrinsically disordered regions), which have been and continue to

While AlphaFold is great, to my knowledge, these proteins have several non-significant IDRs (intrinsically disordered regions), which have been and continue to be hard to model with AlphaFold. I work on computational modeling, so if I had to guess, I'm very unsure if people are using it for whole protein modeling, rather than looking at more specific domains where it probably does much better.