xlrd is going to get Python 3 compatibility: https://github.com/python-excel/xlrd/pull/21 https://github.com/python-excel/xlrd/pull/21 Once that's done, someon

xlrd is going to get Python 3 compatibility: https://github.com/python-excel/xlrd/pull/21 https://github.com/python-excel/xlrd/pull/21 Once that's done, someone has volunteered to add Python 3 support to xlwt as well. openpyxl isn't a direct replacement: it uses the XML-based xlsx format, whereas xlrd/xlwt use the binary xls format.