I personally use Django with disqus for comments. It takes less than an hour to create a decent blog engine in Django if you know the framework, although it too

I personally use Django with disqus for comments. It takes less than an hour to create a decent blog engine in Django if you know the framework, although it took me significantly more than that the first time I did it. With disqus, you can easily add a comment system in seconds. For me, Django was the best choice because I use it for everything else and I really like Python. If you are currently using a more typical LAMP stack, then something like WordPress may be the way to go.