3 ms·

I’m on tirzepatide right now from Eli lily, and I’ve been very interested in Reta, but I can’t say that I jump at the chance to inject something into myself tha

I’m on tirzepatide right now from Eli lily, and I’ve been very interested in Reta, but I can’t say that I jump at the chance to inject something into myself that hasn’t been tested directly on the actual thing I’m about to put into my body. I know there are testing companies that will test certain sources but it’s not like they’ve tested the vial you get. If there’s some kind of pathogen or bacteria or whatever in the vial you get, well, there’s no recourse: it was “for research use only”. That seems like an unacceptable risk, but I see so many people on the internet claiming miraculous results. Maybe if I knew someone in real life, but I know those biohacking subreddits and such are astroturfed to no end by companies looking to sell sketchy peptides.

declan_roberts 2mo ago
That's a common and very acceptable concern and there's not great answers for it. Mostly a place will do multi-vail testing for purity, sterility, endotoxin and heavy metals. The idea is that the sample is sufficient to show safety. Many are rightfully dubious of this but still thousand and thousands of people taking it.
- stephbook 2mo ago
  I'm using reta myself, but honestly it's because sema/tirz isn't allowed for me either. If you have medical tirz available, you should have some serious reasons to jump into the unregulated shark tank.
  - sizzle 2mo ago
    How has it been treating you? Do you keep muscle mass without having to hit 1g/lb of protein intake daily?
    - stephbook 2mo ago
      Haven't measured it exactly, but haven't noticed a reduction in my lifts either. I do have a home gym, throttled my marathon training and try my best with Skyr and protein shakes though.
      - sizzle 2mo ago
        Any idea if a pill form will be available in the future?
        declan_roberts 2mo ago
        Pill form is only available for regular GLP-1, not the double (tirzepatide) and triple agonist (retatrutide).
  - declan_roberts 2mo ago
    A lot of us in tech have CVS Caremark as our pharmacy benefit manager and they will cover Zepbound (tirzepatide) for weight loss in the Fall. The problem is I'm too skinny now to get it!
phil21 2mo ago
> I know there are testing companies that will test certain sources but it’s not like they’ve tested the vial you get. It's why you order a decent amount of it (e.g. 2 years supply, it lasts forever in a freezer) and pay for your own randomized testing of the batch you got. You go direct to the source, not via the middle men selling it for 10x markup on a per-vial basis. Certainly not perfect, and it adds significant cost - but still way cheaper than the regular sources via pharmacy for Zepbound. I'm not convinced reta really shows that greater of results than tirz though. YMMV significantly here. Tirz is already so effective you are chasing marginal gains for the most part.
- sizzle 2mo ago
  It causes less muscle loss/wasting which is a huge benefit over Tirz.

declan_roberts 2mo ago

That's a common and very acceptable concern and there's not great answers for it. Mostly a place will do multi-vail testing for purity, sterility, endotoxin and heavy metals. The idea is that the sample is sufficient to show safety. Many are rightfully dubious of this but still thousand and thousands of people taking it.

stephbook 2mo ago
I'm using reta myself, but honestly it's because sema/tirz isn't allowed for me either. If you have medical tirz available, you should have some serious reasons to jump into the unregulated shark tank.
- sizzle 2mo ago
  How has it been treating you? Do you keep muscle mass without having to hit 1g/lb of protein intake daily?
  - stephbook 2mo ago
    Haven't measured it exactly, but haven't noticed a reduction in my lifts either. I do have a home gym, throttled my marathon training and try my best with Skyr and protein shakes though.
    - sizzle 2mo ago
      Any idea if a pill form will be available in the future?
      - declan_roberts 2mo ago
        Pill form is only available for regular GLP-1, not the double (tirzepatide) and triple agonist (retatrutide).
- declan_roberts 2mo ago
  A lot of us in tech have CVS Caremark as our pharmacy benefit manager and they will cover Zepbound (tirzepatide) for weight loss in the Fall. The problem is I'm too skinny now to get it!

phil21 2mo ago

> I know there are testing companies that will test certain sources but it’s not like they’ve tested the vial you get. It's why you order a decent amount of it (e.g. 2 years supply, it lasts forever in a freezer) and pay for your own randomized testing of the batch you got. You go direct to the source, not via the middle men selling it for 10x markup on a per-vial basis. Certainly not perfect, and it adds significant cost - but still way cheaper than the regular sources via pharmacy for Zepbound. I'm not convinced reta really shows that greater of results than tirz though. YMMV significantly here. Tirz is already so effective you are chasing marginal gains for the most part.

sizzle 2mo ago
It causes less muscle loss/wasting which is a huge benefit over Tirz.