I have used LaTeX for 200+ page documents (various) in the past, so to your question, yes I would. Handing it over to someone else to maintain is a different t

I have used LaTeX for 200+ page documents (various) in the past, so to your question, yes I would. Handing it over to someone else to maintain is a different thing though. Products like InDesign or PageMaker or Word understand that this is what eventually happens in reality. So, the not-so-steep learning curves that WYSIWYG tools offer have won out in the end. If the manual is written by techies, and maintained in-house like all those old Bell Labs manuals that used troff, then markup based typesetting is not such a pain, imho.