4 ms·

One of the many reasons why we should air drop GLP-1 over the entire country, like condoms in Bangladesh!

MrDrMcCoy 3mo ago
Please, no. GLP1s leave you worse off than when you started if you stop taking them. Weight is also not necessarily the factor that leads to sleep apnea; I got diagnosed while having a healthy weight in my 30s.
- Levitz 3mo ago
  >Please, no. GLP1s leave you worse off than when you started if you stop taking them. This doesn't seem factual, or at the very least, not that simple? https://www.epicresearch.org/articles/two-years-after-stopping-glp-1s-most-patients-sustain-at-least-some-weight-loss/ https://www.epicresearch.org/articles/two-years-after-stoppi...
  - 0x20cowboy 3mo ago
    Not the OP, but there was a lot of talk that glp1 had a negative effect on bone density and in older people it was especially problematic. There is evidence that is not the case though https://pmc.ncbi.nlm.nih.gov/articles/PMC8878541/ https://pmc.ncbi.nlm.nih.gov/articles/PMC8878541/
    - Izkata 3mo ago
      Something I'd picked up somewhere a decade or two ago was losing weight too fast can cause problems with bone and muscle density. So it could be related but not a direct effect. I think they were referring to rebound weight though, something else I'd heard about these drugs that also doesn't affect everyone. A scarier one was one person whose weight got too low so they stopped taking it, but for some reason had a lot of trouble gaining any weight and getting up to a healthy level.
    - lukas099 3mo ago
      In old people obesity predicts longer lifespans, so GLP-1 might not be indicated anyway.
ChiperSoft 3mo ago
The satiation effect that GLP-1s cause also affects motivational drive. I've noticed my ability to get work done is hampered when I am at higher doses of my ozempic.
- palmotea 3mo ago
  > I've noticed my ability to get work done is hampered when I am at higher doses of my ozempic. You should be using LLM agents anyway. It's the solution to every problem.
  - yifanl 3mo ago
    Can I have LLMs replace my GLP-1?
    - palmotea 3mo ago
      Yes. LLMs are the new zombo.com. You can do anything with LLMs. Anything at all. The only limit is yourself.
    - canibal 3mo ago
      Bruh, you're not using ChatGLP?
  - ChiperSoft 3mo ago
    If only an LLM could clean my house
SubmarineClub 3mo ago
No thanks, don’t need it, don’t want it!
lazide 3mo ago
Talk about a terrible indictment of western culture if I ever heard of one!
deterministic 3mo ago
GLP-1 has negative side effects (loss of lean mass for example) that I most definitely do not want.

Please, no. GLP1s leave you worse off than when you started if you stop taking them. Weight is also not necessarily the factor that leads to sleep apnea; I got diagnosed while having a healthy weight in my 30s.

Levitz 3mo ago
>Please, no. GLP1s leave you worse off than when you started if you stop taking them. This doesn't seem factual, or at the very least, not that simple? https://www.epicresearch.org/articles/two-years-after-stopping-glp-1s-most-patients-sustain-at-least-some-weight-loss/ https://www.epicresearch.org/articles/two-years-after-stoppi...
- 0x20cowboy 3mo ago
  Not the OP, but there was a lot of talk that glp1 had a negative effect on bone density and in older people it was especially problematic. There is evidence that is not the case though https://pmc.ncbi.nlm.nih.gov/articles/PMC8878541/ https://pmc.ncbi.nlm.nih.gov/articles/PMC8878541/
  - Izkata 3mo ago
    Something I'd picked up somewhere a decade or two ago was losing weight too fast can cause problems with bone and muscle density. So it could be related but not a direct effect. I think they were referring to rebound weight though, something else I'd heard about these drugs that also doesn't affect everyone. A scarier one was one person whose weight got too low so they stopped taking it, but for some reason had a lot of trouble gaining any weight and getting up to a healthy level.
  - lukas099 3mo ago
    In old people obesity predicts longer lifespans, so GLP-1 might not be indicated anyway.

ChiperSoft 3mo ago

The satiation effect that GLP-1s cause also affects motivational drive. I've noticed my ability to get work done is hampered when I am at higher doses of my ozempic.

palmotea 3mo ago
> I've noticed my ability to get work done is hampered when I am at higher doses of my ozempic. You should be using LLM agents anyway. It's the solution to every problem.
- yifanl 3mo ago
  Can I have LLMs replace my GLP-1?
  - palmotea 3mo ago
    Yes. LLMs are the new zombo.com. You can do anything with LLMs. Anything at all. The only limit is yourself.
  - canibal 3mo ago
    Bruh, you're not using ChatGLP?
- ChiperSoft 3mo ago
  If only an LLM could clean my house

SubmarineClub 3mo ago

No thanks, don’t need it, don’t want it!

lazide 3mo ago

Talk about a terrible indictment of western culture if I ever heard of one!

deterministic 3mo ago

GLP-1 has negative side effects (loss of lean mass for example) that I most definitely do not want.