2 ms·

Anyone got a quick primer on what 7-Oh is? That's a new term for me and the web search doesn't seem reliable.

by hoistbypetard 2mo ago

ChrisArchitect 2mo ago
https://en.wikipedia.org/wiki/7-Hydroxymitragynine https://en.wikipedia.org/wiki/7-Hydroxymitragynine
simulator5g 2mo ago
Synthetic opioids sold at gas stations.
- switchbak 2mo ago
  Here in Canada you're not allowed to 3d print a modded grip for the rifle you're not allowed to buy, but in the USA you can get OPIOIDS at a GAS STATION! ... things are definitely different down there.
  - mothballed 2mo ago
    But the prison sentence once caught is much shorter in Canada.
    - switchbak 2mo ago
      The prison sentence for being caught doing legal things is surprisingly short.
  - mghackerlady 2mo ago
    To be fair, it is a relatively weak one that people claim has medicinal benefits
IAmGraydon 2mo ago
Kratom is a leaf that is primarily farmed in Asia which contains the active ingredient Mitragynine, which has some very mild partial-agonist opioid effects. When kratom is consumed, your liver converts a very small amount to a MUCH more potent molecule called 7-hydroxymitragynine. As with all natural drugs, some asshats in a lab decided to figure out how to create the latter molecule semi-synthetically and in bulk. They pressed them into pills and sell them in head shops and some gas stations. It's pretty addictive, nasty stuff.
milesvp 2mo ago
I first learned of kratom in the last year from Elijah Lemard https://www.youtube.com/watch?v=0z5ixJIqbGY&t=267s https://www.youtube.com/watch?v=0z5ixJIqbGY&t=267s He's an odd guy who likes to investigate some really dodgy stuff. And I suspect many here on HN would appreciate him. That led to 7-OH showing up in my feed at some point. In a nutshell, it's the strongest of the active compounds in the kratom plant, that binds to opioid receptors. 7-OH is the marketing name for the alkaloid 7-hydroxymitragynine that is being refined from kratom. It's not clear to me if it's simply extracted, or as some quick research suggests, it might also be a chemical alteration of the more commonly occurring compound in kratom mitragynine. Anyway, this stuff looks super habit forming, and, of course, the refined version is that much more addictive.
dijksterhuis 2mo ago
recent jon oliver last week tonight segment on kratom and the wider 7-oh stuff. Gas Station Drugs: Last Week Tonight with John Oliver (HBO) https://www.youtube.com/watch?v=mRZqHzDG_c8 https://www.youtube.com/watch?v=mRZqHzDG_c8 > John Oliver discusses the sprawling industry of “gas station drugs” – a world of questionable supplements and boner pills – which is posing a risk to the public by putting underregulated substances over the counter, and, more importantly, could prevent people from saving up for a Honda Civic.

Anyone got a quick primer on what 7-Oh is? That's a new term for me and the web search doesn't seem reliable.

ChrisArchitect 2mo ago

https://en.wikipedia.org/wiki/7-Hydroxymitragynine https://en.wikipedia.org/wiki/7-Hydroxymitragynine

simulator5g 2mo ago

Synthetic opioids sold at gas stations.

switchbak 2mo ago
Here in Canada you're not allowed to 3d print a modded grip for the rifle you're not allowed to buy, but in the USA you can get OPIOIDS at a GAS STATION! ... things are definitely different down there.
- mothballed 2mo ago
  But the prison sentence once caught is much shorter in Canada.
  - switchbak 2mo ago
    The prison sentence for being caught doing legal things is surprisingly short.
- mghackerlady 2mo ago
  To be fair, it is a relatively weak one that people claim has medicinal benefits

IAmGraydon 2mo ago

Kratom is a leaf that is primarily farmed in Asia which contains the active ingredient Mitragynine, which has some very mild partial-agonist opioid effects. When kratom is consumed, your liver converts a very small amount to a MUCH more potent molecule called 7-hydroxymitragynine. As with all natural drugs, some asshats in a lab decided to figure out how to create the latter molecule semi-synthetically and in bulk. They pressed them into pills and sell them in head shops and some gas stations. It's pretty addictive, nasty stuff.

milesvp 2mo ago

I first learned of kratom in the last year from Elijah Lemard https://www.youtube.com/watch?v=0z5ixJIqbGY&t=267s https://www.youtube.com/watch?v=0z5ixJIqbGY&t=267s He's an odd guy who likes to investigate some really dodgy stuff. And I suspect many here on HN would appreciate him. That led to 7-OH showing up in my feed at some point. In a nutshell, it's the strongest of the active compounds in the kratom plant, that binds to opioid receptors. 7-OH is the marketing name for the alkaloid 7-hydroxymitragynine that is being refined from kratom. It's not clear to me if it's simply extracted, or as some quick research suggests, it might also be a chemical alteration of the more commonly occurring compound in kratom mitragynine. Anyway, this stuff looks super habit forming, and, of course, the refined version is that much more addictive.

dijksterhuis 2mo ago

recent jon oliver last week tonight segment on kratom and the wider 7-oh stuff. Gas Station Drugs: Last Week Tonight with John Oliver (HBO) https://www.youtube.com/watch?v=mRZqHzDG_c8 https://www.youtube.com/watch?v=mRZqHzDG_c8 > John Oliver discusses the sprawling industry of “gas station drugs” – a world of questionable supplements and boner pills – which is posing a risk to the public by putting underregulated substances over the counter, and, more importantly, could prevent people from saving up for a Honda Civic.