3 ms·
Unfortunately this is a spurious finding. See this presentation: https://youtu.be/qlTnnQytOJ0 https://youtu.be/qlTnnQytOJ0 The mechanism is that people with th
by modeless 3mo ago
Unfortunately this is a spurious finding. See this presentation: https://youtu.be/qlTnnQytOJ0 https://youtu.be/qlTnnQytOJ0
The mechanism is that people with the shingles vaccine are less likely to visit the hospital (because they don't get shingles). Because they have fewer hospital visits they are less likely to receive an incidental diagnosis of dementia from a hospital.
- teravor 3mo agoare there that many instances of mild dementia where a lack of diagnosis remains a lack?
- asdff 3mo agoWell it does tend to happen late in life where other health issues could take you out before the dementia gets noticeable beyond usual senility.
- dlcarrier 3mo agoThere's also this whole thing: https://xkcd.com/882/ https://xkcd.com/882/ There's countless treatments and countless diseases. It is very much worth combing data to find treatments with potential off-label uses, but with that many combinations of treatments and diseases, much more care needs to go into eliminating not just non-causative correlations, but straight-up random correlations that have a very small probability of happening on their own, but are likely to happen in a large enough group of comparisons.
- cubefox 3mo agoYes, though the above only addresses studies based on Zostavax. Shingrix might still offer some protection from dementia.