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> I can nearly eliminate cholesterol in mice "Cholesterol" is an organic compound that is essential for life. What exactly do you mean you can nearly eliminate
by awolf 14y ago
> I can nearly eliminate cholesterol in mice
"Cholesterol" is an organic compound that is essential for life. What exactly do you mean you can nearly eliminate it in mice?
- deleted 14y ago[deleted]
- carbocation 14y agoOf course you're right; I'm using colloquial shorthand. I'm referring to apolipoproteins bound to lipids and cholesterol (at which point we can call them lipoproteins). What I really am talking about is VLDL-cholesterol, LDL-cholesterol, HDL-cholesterol, and triglycerides. awolf's challenge is particularly relevant and on-point because extremely low levels of LDL-cholesterol from birth (hypobetalipoproteinemia or abetalipoproteinemia) is associated with neurological deficits. When caused by defective APOB, it is also associated with non-alcoholic fatty liver disease.
- Devilboy 14y agoWhat is the function of LDL (bad?) cholesterol in the body?
- carbocation 14y agoA simple and generally correct statement: LDL particles deliver cholesterol from the liver to the cells throughout your body. Cholesterol is water insoluble, so it needs a carrier; the apolipoproteins (ApoB, which is the key protein component of VLDL and LDL) are those carriers.