I think that Seattle would be a great place to have your first office - you get access to local talent from companies like Amazon, Microsoft and Valve. But also

I think that Seattle would be a great place to have your first office - you get access to local talent from companies like Amazon, Microsoft and Valve. But also, when it comes time to set up your second office, you can do that in Vancouver. Then you can hire international employees and take advantage of Canada's more friendly immigration policies to relocate them to Vancouver. And then when you need to have in-person contact, Vancouver is just a 2.5 hour drive from Seattle, and all the American citizens working in Seattle can easily hop the border for any such meetings.