4 ms·

Nice, maybe it balances out nicotine. People who don't pair caffeine with nicotine simply have no clue what they are missing ;)

neya 5mo ago
> People who don't pair caffeine with nicotine simply have no clue what they are missing ;) We do, and that's called cancer;)
- jonnybgood 5mo ago
  Is there research that links nicotine to cancer? I’m unable to find anything that would suggest nicotine as cancer causing.
  - cf100clunk 5mo ago
    Are you researching whether you'll get cancer if you are extracting 100% pure nicotine and ingesting it? Who does that?
    - steve_adams_86 5mo ago
      A lot of people consume nicotine. It has been isolated and used in products for a long time. There's no clear link to cancer, but it could impact cardiovascular health (like all stimulants seem to). Some research indicates that nicotine can influence how existing cancer behaves and spreads, so that's worth considering.
      - cf100clunk 5mo ago
        Right, point taken, but I wasn't following how nicotine properties were connected to coffee's health benefits.
        Tagbert 5mo ago
        zingababba started this thread talking about mixing caffeine and nicotine.
        christophilus 5mo ago
        He was suggesting— jokingly— that maybe coffee cancels out the deleterious effects of smoking, because indeed coffee + a cigar or pipe is truly an excellent experience.
        steve_adams_86 5mo ago
        Mentat-mode engaged
    - coffeebeqn 5mo ago
      Most nicotine users today? Everyone’s using the pure nicotine pouches like zyn and such. I didn’t really find it enjoyable at all
      - raducu 5mo ago
        > Most nicotine users today? I did use pure nicotine and it was very bad for my health, probably due to high dosage, but still. I've used heavy stimulants, benzos, opioids, dissociatives without an issue, but nicotine is in a class of its own in terms of how insidiously addictive it is. But just from a health point of view: extreme arm and hand joint issues, forearm vascular issues that made my hands numb at night, palpitations/arrithmia like I was about to die when I used nicotine before sleep and I was drifting to sleep -- it really felt like I was about to die, like my heart was mangled up.
- gavmor 5mo ago
  It's the endothelial dysfunction, oxidative stress, increased arterial stiffness, and accelerated atherosclerosis that turn me off.
soupspaces 5mo ago
[dead]
sfpotter 5mo ago
"Serious delirium!"
maximinus_thrax 5mo ago
I quit smoking a long time ago but if there's one thing I'm missing / craving is a hot cup of coffee with two cigarettes on an empty stomach during cold winter mornings... Fuuuuck.

neya 5mo ago

> People who don't pair caffeine with nicotine simply have no clue what they are missing ;) We do, and that's called cancer;)

jonnybgood 5mo ago
Is there research that links nicotine to cancer? I’m unable to find anything that would suggest nicotine as cancer causing.
- cf100clunk 5mo ago
  Are you researching whether you'll get cancer if you are extracting 100% pure nicotine and ingesting it? Who does that?
  - steve_adams_86 5mo ago
    A lot of people consume nicotine. It has been isolated and used in products for a long time. There's no clear link to cancer, but it could impact cardiovascular health (like all stimulants seem to). Some research indicates that nicotine can influence how existing cancer behaves and spreads, so that's worth considering.
    - cf100clunk 5mo ago
      Right, point taken, but I wasn't following how nicotine properties were connected to coffee's health benefits.
      - Tagbert 5mo ago
        zingababba started this thread talking about mixing caffeine and nicotine.
      - christophilus 5mo ago
        He was suggesting— jokingly— that maybe coffee cancels out the deleterious effects of smoking, because indeed coffee + a cigar or pipe is truly an excellent experience.
        steve_adams_86 5mo ago
        Mentat-mode engaged
  - coffeebeqn 5mo ago
    Most nicotine users today? Everyone’s using the pure nicotine pouches like zyn and such. I didn’t really find it enjoyable at all
    - raducu 5mo ago
      > Most nicotine users today? I did use pure nicotine and it was very bad for my health, probably due to high dosage, but still. I've used heavy stimulants, benzos, opioids, dissociatives without an issue, but nicotine is in a class of its own in terms of how insidiously addictive it is. But just from a health point of view: extreme arm and hand joint issues, forearm vascular issues that made my hands numb at night, palpitations/arrithmia like I was about to die when I used nicotine before sleep and I was drifting to sleep -- it really felt like I was about to die, like my heart was mangled up.
gavmor 5mo ago
It's the endothelial dysfunction, oxidative stress, increased arterial stiffness, and accelerated atherosclerosis that turn me off.

soupspaces 5mo ago

[dead]

sfpotter 5mo ago

"Serious delirium!"

maximinus_thrax 5mo ago

I quit smoking a long time ago but if there's one thing I'm missing / craving is a hot cup of coffee with two cigarettes on an empty stomach during cold winter mornings... Fuuuuck.