3 ms·
Ah causal data! It’s a shame none of the scientists or statisticians thought of getting causal data. How would we get that? Well maybe we could just inject amyl
by bglazer 5mo ago
Ah causal data! It’s a shame none of the scientists or statisticians thought of getting causal data. How would we get that? Well maybe we could just inject amyloid into a person’s brain. Or simply remove all the amyloid from a person’s brain. That should do it, right?
I mean an amyloid injection is wildly unethical and it’s also not the natural progression of Alzheimer’s. Removing amyloid is a simple matter of investing billions of dollars into drug development. Also how do you tell whether that was actually “causal” if the patients improve after plaque removal.
I mean come on, you have to work the evidence and the experimental tools that we actually have. This kind of epistemic puritanism doesn’t help anyone.
- bsder 5mo ago> Well maybe we could just inject amyloid into a person’s brain. Erm, we kinda did? People who got cadaver-derived human growth hormone from Alzheimer's patients got Alzheimer's. https://www.nature.com/articles/s41591-023-02729-2 https://www.nature.com/articles/s41591-023-02729-2 And we just had an actual autopsy confirm a case: https://www.medscape.com/viewarticle/new-evidence-strengthens-case-iatrogenic-alzheimers-2026a1000ah9 https://www.medscape.com/viewarticle/new-evidence-strengthen...