To add some context on the study I linked - that particular study was only focused on understanding why, after decades of use by humans as a supplement, that li

To add some context on the study I linked - that particular study was only focused on understanding why, after decades of use by humans as a supplement, that lithium orotate has so rarely been reported in any cases of adverse effects (all the cases I could find were acute toxicity from taking way too much, like the 18 year old woman who took 18 capsules at once, and still only suffered nausea and some mild tremors). So that study found none of the effects on specific organ systems in rats that you often find in other substances that have higher rates of adverse effects. My point being, if that was the only safety study done on a brand new substance, I'd agree with you, but the safety profile really boils down to the decades of human use as a supplement. All that said, I totally agree that many more human studies are needed to determine the actual efficacy of lithium orotate in preventing or reversing dementia.