4 ms·
... which kind of points to the indicator that "Alzheimer != Alzheimer", implying that too many diseases with the same side effects are categorized together? A
by cookiengineer 6mo ago
... which kind of points to the indicator that "Alzheimer != Alzheimer", implying that too many diseases with the same side effects are categorized together?
A lot of virological and parasitical components have historically been wrongly associated with genetic markers, too. Toxoplasmosis parasite comes to mind.
[1] https://en.wikipedia.org/wiki/Toxoplasmosis https://en.wikipedia.org/wiki/Toxoplasmosis
[2] https://en.wikipedia.org/wiki/Toxoplasma_gondii https://en.wikipedia.org/wiki/Toxoplasma_gondii
- josh-wrale 6mo agoNon-sequitur
- DANmode 6mo agoNon-diagnostician
- josh-wrale 6mo agoPoint stands.
- DANmode 6mo agoSo does the lack of a model for Alzheimer’s, and other chronic illnesses, that the consumer-facing medical industry prefers to dismiss.
- josh-wrale 6mo agoI didn't argue a model beyond one cause.
- anon84873628 6mo agoThe tau hypothesis is looking like a good model.
- cookiengineer 6mo ago> Non-sequitur Not sure what you are trying to achieve with comments like this, besides intentional gas lighting. Could've commented with links to scientific articles or papers that disprove my theory. Instead you chose to be ... this?
- josh-wrale 6mo agohttps://med.stanford.edu/news/insights/2025/09/rethinking-alzheimers-gene-variant-apoe4.html https://med.stanford.edu/news/insights/2025/09/rethinking-al...
- cookiengineer 6mo agoYou do realize that they are referring to the same study and dataset, which showed that shingles is correlated to APOE4, right? Not sure if you are trolling at this point.
- josh-wrale 6mo agoI am not a researcher in this field. I have read a lot about APOE4, and nearly everything I have seen about APOE4 makes it out to be the clearest of all predictors for Alzheimer's. I get that you're upset that I posted like I did, but I am not trolling. The point was that genetic causes are not an exceptional predictor for Alzheimer's. I had a hard time seeing how the best established predictor for Alzheimer's validates there being too many things labeled as Alzheimer's. If I had posted with a focus on some edge case, then it probably would have made more sense to me, but as I read it, it really seemed like a stretch. Dropping this thread now. I am fine with being wrong, but my brief posting was not trolling.