5 ms·
A Collection of Chronic Medical Conditions Common in Autistic and ADHD Adults [pdf] (2023)
- deleted 6mo ago[deleted]
- blakesterz 6mo ago[flagged]
- FrustratedMonky 6mo ago"This resource is intended as an introductory primer for primary care clinicians" Anybody have a more non-medical-background summary?
- giantg2 6mo agoI would have loved a more readable format at least. It's lumping groups of issues together and it's hard to track specific conditions to their source paper and other details.
- bcjdjsndon 6mo agoIt's part of the current of poor quality research around autism and ADHD, often conflating them into unique condition Audhd.
- Lowgain 6mo agoI think AuDHD is meant to describe having both Autism and ADHD, not conflating them into a single condition
- permalac 6mo agoThat is correct.
- bcjdjsndon 6mo agoAutism is a spectrum but audhd seems only to apply to the non-severe end
- Aurornis 6mo agoThis document would never be taken seriously by any good medical professional. The website it’s hosted on is trying to sell neurodiversity trainings to businesses. They link to YouTube videos of their webinars when they cite their “lived experiences” as their background credentials. This is really bad information. I suggest not getting involved in this side of medical misinformation that springs primarily from parts of social media but is being dressed up as if it’s just a helpful medical resource.
- bluefirebrand 6mo agoI've been learning a lot about this sort of thing. I was diagnosed with ADHD in 2020 or so, and just the past August was also diagnosed with celiac. It seems that there's some pretty strong correlation between the two.
- olyjohn 6mo agoI was noticing the other day how my pollen allergies would subside when I took some Adderall, and would come back when it wore off. I looked it up and there are actually correlations between allergies and ADHD. I'm not sure if Celiac is the same kind of allergy or not, but I thought it was interesting.
- Aurornis 6mo ago> I was noticing the other day how my pollen allergies would subside when I took some Adderall, and would come back when it wore off. The explanation is much more simple: Adderall is amphetamine, which has functional overlap with how pseudoephedrine (aka Sudafed) works. They are both norepinephrine releasing agents. Pseudoephedrine is considered a substituted amphetamine in chemistry lingo.
- SummSolutions 6mo agoExtremely important information. Other connective tissue disorders can also present with these findings.
- cjbgkagh 6mo agoThis is great, check my post history, I've been beating this drum for many years now. hEDS is very very very under-diagnosed and this one simple fact is sufficient to explain a the prevalence of a whole zoo of seemingly unrelated conditions. There is an incentive to keep hEDS as a 'rare' disease as the US has extra grants for disease in this classification and this has put pressure on diagnostic criteria which was made more strict so fewer people would be diagnosed with it. I'm about to head out for lunch so this will have to be a shorter post but I'll touch on some of the major points. * The progression of prevalence of hEDS over the years has gone from 1/50K, 1/15k, 1/5k, to 1/500 which is insane. Most people are using values from older studies so they think it is much rarer than it actually is. * I don't see a strong distinction between hEDS and HSD, diagnosis appears to be mainly a matter of severity but due to that being rather random there isn't a clear distinction. * The TNXB gene is overlooked because too many people have SNPs here and the assumption of the rarity of hEDS rules it out. It seems that number and type of TNXB SNPs as well as other RCCX genes also govern severity. * If you look at long covid information the proportion of those who have hEDS/HSD is far higher than it should be. Dr Jessica Eccles has great research on this, I think the obvious explanation here is far more people have hEDS/HSD than have been diagnosed with it, and these conditions create a strong predisposition to ME/CFS/LongCovid. * Average time to diagnosis is 20 years from the onset of symptoms, which is insane, but it gets worse when you consider that the vast majority with it never get diagnosed, so the average is really never. I have a rather severe form of this and even I would have a hard time getting diagnosed with hEDS - I look too healthy. I've never been formally diagnosed but have a Whole Genome Sequence with the expected TNXB SNPs. Things that I've tried and worked; * Low Dose Naltrexone (LDN) is a great start (mentioned here in the pdf) * Supplemental T3 as sub-clinical hypothyroidism is pretty common * I think a combination of weak ligands like Modafinil and Amitriptyline can really help with dysautonomia * I take low dose of semiglutide and this seems to help with the auto-immune aspect * I take Ipa/ModGRF(no dac), BPC157/TB5, and VIP * High dose TUDCA and high dose DIM * Supplemental testosterone * Zero sugar diet, including no fruit. I basically subsist on kale salads and steak.
- verisimi 6mo agohEDS - Hypermobile Ehlers-Danlos Syndrome, I think. "Hypermobile Ehlers-Danlos syndrome (hEDS) is a heritable connective tissue disorder that causes generalized joint hypermobility, joint instability, and chronic pain." HSD - Hypermobility spectrum disorder. "Hypermobility spectrum disorders are a group of heritable connective tissue disorders where joints are flexible enough to cause problems such as instability and pain."
- virtualritz 6mo agoThis is a stark reminder why you use LaTex or typst with a good template for typesetting your scientific contributions. Unless you learned basic typography that is. This eyesore looks like it was done in Word & Co. What a pity, given what a treasure trove this is. As someone with a partner who has ADHD I think this should be mandatory reading for any GP.
- deleted 6mo ago[deleted]
- Aurornis 6mo ago> for typesetting your scientific contributions. This is not a scientific contribution. It's basically a pamphlet for a group of people selling "neurodiversity trainings" for organizations.
- analog8374 6mo agoAutism and ADHD are a (deep) habit of the attention. A habit of moving the attention in a way that is possibly unhealthy, unuseful and probably discordant to what's common and normal. One solution is to change that habit with drugs or therapy. Another solution is to gain a greater understanding of your attention. Thus gaining a new freedom to move your attention in whatever way, rather than suffering the governance of habit. The meditation people (Buddhists etc) study attention. They have some impressive methods and such. It's worth looking.
- IncreasePosts 6mo agoWhat do meditation people do with their great powers of attention? Besides for naval gazing of course.
- analog8374 6mo agoThey study it, thus gaining a better understanding of it. They become more familiar with it, thus replacing habit with intelligence. This leads to increased power and freedom, among other things.
- estimator7292 6mo agoYou should study autism and the people around you instead of your own navel. Clearly you don't at all understand what it is to be autistic or ADHD. Have you ever tried talking to an autistic person?
- analog8374 6mo agoas a matter of fact I have
- DANmode 6mo agoWhat do all the jungle civilizations and any possible intelligent extraterrestrial life do? Stay away from us to their own benefit, of course.
- 6mo ago
- nkoren 6mo agoOn the off-chance that psychosomatic suggestibility is on this list, I'm not even looking at it.
- wizzwizz4 6mo agoPsychosomatic suggestibility is not on the list. These are also all chronic conditions, so if the descriptions don't match your history, you have nothing to worry about.
- cjbgkagh 6mo agoThough statistically if you’ve previously been told you have something psychosomatic the odds are pretty good that you have something on this list.
- Aurornis 6mo agoUnfortunately this document and the linked YouTube videos uses the social media definitions of these conditions, so readers could be misled into thinking they have conditions which they don’t. The article is really bad. I do not suggest anyone take it seriously.
- wizzwizz4 6mo agoYeah… I skipped the first page, in order to quickly answer the question. Shouldn't have done that. (While one should never judge a book by its cover in the metaphorical sense, it's actually quite sensible to make such judgements in the literal sense.)
- oytis 6mo agoWhat's the context for that, I don't get it
- estimator7292 6mo agoHypochondria is really common among autistic people. To the point that it's an in-joke and meme among the community.
- deleted 6mo ago[deleted]
- latein 6mo agoHypermobility can lead to Osteoarthritis in later life also.
- Rekindle8090 6mo agoI think this has nothing to do with commonality and more to do with the fact everyone I know who is autistic (I work in tech) has been obsessively getting themselves diagnosed with things since they were like 14 like its a religion. Just has a new thing wrong with them weekly
- DANmode 6mo agoEverything looks like a conspiracy|hypochondria, when you understand nothing.
- estimator7292 6mo agoWhen people constantly dismiss and mock you like this, treat you like you're the problem, it creates a deep need to find an explanation and justification. You should try harder to treat autistic people like people, instead of mocking and dismissing things you can't be bothered to try understanding. Comorbidity is a very real thing. Autistic people do have high incidence of comorbid conditions. Your narrow view of the world does not represent universal truth. Hypochondria is common among autistic people, because they commonly have real issues. When everyone refuses to take you seriously, you have to find your own answers. You're the problem here, bud.
- rigrassm 6mo ago> I think this has nothing to do with commonality and more to do with the fact everyone I know who is autistic (I work in tech) has been obsessively getting themselves diagnosed with things since they were like 14 like its a religion. I hope you decide to keep that opinion to yourself in the future and not tell people that what they are experiencing isn't real. > Just has a new thing wrong with them weekly So, you see multiple people experiencing a new medical ailment or symptom "every week" and think all these people are faking an issue so well it fools a doctor? What about my severe plaque psoriasis, T-1 Diabetes, and POTS? Am I just imagining the giant red inflamed scaly patches of skin on each one of my joints? Am I just psychosomatically making my body not produce insulin? Im just making up that my blood pressure drops so low from standing too fast that I get tunnel vision? Your opinion causes people like me to spend 20 years of their life to hide and ignore the problems they experience until they are so bad we can't function as human beings anymore. And the sad part of it is, if we (the patients) actually understood what we were dealing with early on in life, a lot of these problems can be avoided. It's a shame so many people share your ignorant opinion and tendency to shame what you can't understand, you'll never comprehend how deeply that effects the people you are saying it about.
- Aurornis 6mo agoIf this PDF isn't triggering your skepticism, you need to adjust your sensitivity for pseudoscience. It's a PDF put together by an organization that sells "neurodiversity trainings for organizations". They try to lend legitimacy by linking to papers describing conditions, but their claim that these are all a "cluster" just goes to a YouTube video of their own webinar where they discuss their "lived experiences" as the basis for their claims. The document mixes science with pseudoscience. It was put together by someone who subscribes to the current social media trends that blend together real diagnoses in a way that have been distorted and stretched to become generic catch-all explanations for vague conditions This mess where conditions like MCAS, hEDS, POTS, and ADHD are all swirled together into a cluster of co-diagnoses is becoming a huge problem on social media. Even the individual groups for these conditions are become sick of the trend of pushing them all as co-diagnosis. One example from the ME/CFS forums sampling the frustration with how people incorrectly self-diagnosing with all of these conditions as a cluster is becoming a problem for each individual condition: https://www.s4me.info/threads/problems-arising-for-pwme-from-additional-diagnoses-of-mcas-heds-and-pots-advocacy-discussion.48187/ https://www.s4me.info/threads/problems-arising-for-pwme-from... This should be flagged away as it's both misinformation and a document serving as a lead gen for their training services based on misinformation (see the link at the bottom of the document)
- wizzwizz4 6mo agoThe whole "clustering" thing is nonsense, but there is a real thing, known as "multimorbidity". There are conditions that are often found together, such that if you diagnose one, it's worth checking for the others. This isn't because the conditions are the same, but because some causal phenomenon (usually developmental) creates the circumstances for more than one condition. Premature birth appears somewhere in the causal network in a lot of cases, as does poverty. (I'm pretty sure poverty's a cause, though premature birth might be a result of the circumstances, rather than a cause.) On that note, Wikipedia has a much better list than this PDF: https://en.wikipedia.org/wiki/Conditions_comorbid_to_autism https://en.wikipedia.org/wiki/Conditions_comorbid_to_autism. (This list is not without its flaws, but I at least find it easier to compensate for academic ignorance than magical thinking.) Also related is differential diagnosis, which is a process by which clinicians distinguish between different diagnoses that have overlapping symptoms. (It's not a particular fancy technique, it's literally just the name for any approach that does that.)
- GoodOldNe 6mo agoThis is Sick-Tok's greatest hits. I am a former special education teacher and current emergency medicine physician and have tremendous compassion for those who are truly dealing with life-limiting conditions like ASD and real EDS (the kind that causes aortic dissections among other very serious kinds of pathology). I simultaneously have compassion for those who are suffering physically and psychically and who want an explanation and a label and for some reason find their way towards wanting to identify as chronically ill / disabled. It's a tough thing but from what I have seen, pursuing the diagnoses on this list makes life worse for the vast majority of people who choose to do so. There is a rapidly expanding cottage industry of charlatans who will diagnose and treat these things, and others who post about them online and feed the cycle. I'll admit spectrum bias, since I see the ones who come to the ER with concern about these issues and they skew hard in a certain direction but this is overall not a good thing.
- DANmode 6mo agoUntil you and your colleagues derive the root cause of an individual’s chronic suffering (or the patient jumps ship and has naturopathy do so), then they are chronically ill or disabled. They don’t want to be: most just want to be recognized as what they are long enough to find the path out. or any optimization.