The world of the very small is a very strange place https://en.wikipedia.org/wiki/Disappearing_polymorph https://en.wikipedia.org/wiki/Disappearing_polymorph W

The world of the very small is a very strange place https://en.wikipedia.org/wiki/Disappearing_polymorph https://en.wikipedia.org/wiki/Disappearing_polymorph We can't make a certain HIV drug anymore because after 2 years, a lower energy crystal state formed, and that state isn't as effective. Now anytime we try to form synthesize the drug it finds a molecule of the lower energy crystal state which causes the crystal to also form in the lower energy state.