3 ms·
If a lot of people take the mediation and die is that evidence that the medication is unsafe? If they live is that evidence that the medication is safe? Either
by cjbgkagh 7mo ago
If a lot of people take the mediation and die is that evidence that the medication is unsafe? If they live is that evidence that the medication is safe? Either both are true or neither is true. The relative weight of evidence is dependent on priors but it is still evidence.
- dotancohen 7mo agoYour comment reads like someone with no experience in medical trials - neither pharmaceutical nor medical devices. Death is not the only negative outcome. Nor is a procedure that is commonly followed by death necessarily a bad procedure - many cancer treatments for example fall into this category.
- cjbgkagh 7mo agoYou’re not understanding the point of the hypothetical, it was to illustrate a scenario in that most people would consider evidential and point out that by definition the opposite outcome must also be evidential even if that outcome was far more likely. It’s to highlight an unintuitive aspect of probability formalized as the bayes ratio. The strength of the evidence is dependent on the priors but it exists. Anecdotal evidence is not zero evidence it is weak evidence and with care a lot of anecdotal evidence can be combined to create stronger forms of evidence. Rounding it down to zero or up to one are both incorrect.
- dotancohen 7mo agoAnd yet neither of the sides are strong enough to term as evidence. I have no problem with self-experimentation. But citing a few anecdotes as evidence is a dangerous area that I discourage. Somedau we will understand why some people respond so favourably to the wolverine stack and others don't. And somebody will someday correlate what those hurt by BPC-157 all have in common. But until then, these peptides cannot be recommended to others in good conscious. But for self-use? Go right ahead.
- aminocore 6mo ago[dead]