It's not even just 3d printing skill, but understanding the physiology of how the bone and teeth will restructure themselves over time to know the right amount

It's not even just 3d printing skill, but understanding the physiology of how the bone and teeth will restructure themselves over time to know the right amount of pressure to apply to encourage that remodeling, without so much pressure to cause damage - there is a huge amount of scientific research there! (That I'm sure some orthodontists probably pay more detailed attention to than others). I don't doubt a high-IQ high functioning autist could self-teach this, but there's a ton of background there.