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> Currently, the most plausible theory emerging from her team’s research points to metabolism: Healthy and cancerous cells may process reactive oxygen species—u
by slibhb 8mo ago
> Currently, the most plausible theory emerging from her team’s research points to metabolism: Healthy and cancerous cells may process reactive oxygen species—unstable oxygen-containing molecules generated during radiation—in very different ways.
Reminds me of this which I (think) was linked here a while ago: https://www.nature.com/articles/s12276-020-0384-2 https://www.nature.com/articles/s12276-020-0384-2
It really does feel like all these piecemeal cancer treatments are converging on something resembling a cure.
- hinkley 8mo agoThere was also a study that showed that chemotherapy efficacy was enhanced by fasting before treatment. It seems that when calories are scarce, healthy cells turtle up while cancer cells keep consuming, so fasting reduces absorption rates in healthy tissues and thus collateral damage.
- sl_convertible 8mo agoHealthy cells CAN turtle-up, whereas cancer cells engage in unregulated reproduction. Also, some cancer cells can only consume glucose. Which, in a fasted state, would mean that the majority of energy would be in ketones(if the individual were metabolically healthy), starving the cancer cells to death.
- arijun 8mo agoWhy wouldn’t a strict keto diet not be a cure for those cancers?
- nick__m 8mo agoBecause the cancers cells adapt! (fast reproduction and high mutation rate of the cancerous cells make that process quicker than antibiotics resistance)
- m_rcin 8mo agomany people try it, but the results are mixed.
- sl_convertible 8mo agothe body will actually turn protein into glucose, so the body will never be completely glucose free.
- cyberax 8mo agoThere was a study that chemotherapy works best in the _morning_. Derek Lowe had an article about this:
- cyberax 8mo agoD'oh. Forgot to add the link: https://www.science.org/content/blog-post/get-early-start https://www.science.org/content/blog-post/get-early-start
- spopejoy 8mo agoPlease don't throw around random "a study that showed" about cancer treatments and chemotherapy. If you really think it needs to be shared, share the study and while you're at it, check in with a good oncologist or knowledgeable friend too. In my ~10 years of enduring chemo and other treatments, the amount of garbage you have to wade through from "well meaning" anecdata like "wheat grass" or "smoke huge bongloads" or "don't eat sugar" makes an already horrible process worse. And yes I checked this with my onc at MSK. Dietary glucose in particular -- if you cut out enough sugar to starve cancer cells you would be doing lots of damage elsewhere as well.
- hinkley 8mo agoYou’re talking about elimination diets, I’m talking about skipping a meal.
- spopejoy 8mo agoI'm saying that cancer treatments are some of the most scientifically-validated procedures out there, because there's essentially unlimited money to pay for them. They have eliminated or modulated any negative side effect they can, via improved anti-nausea drugs, careful dosing+timing, etc. Still, you can experience all sorts of discomforts during the tmt. I nearly fainted and got horrible chills when getting oxaliplatin for the first time. You're saying I should have _fasted_ for this?
- amanaplanacanal 8mo agoPeople eat keto diets all the time. What damage do you think they are doing to themselves?
- defrost 8mo agoThe damage risked by Keto diets includes nutrient deficiency, liver and kidney problems, constipation, fuzzy thinking and mood swings. Of these risks it's the potential veering into liver and kidney problems that deserves the closest monitoring. See: https://www.health.harvard.edu/staying-healthy/should-you-try-the-keto-diet https://www.health.harvard.edu/staying-healthy/should-you-tr... ~ Howard E. LeWine, MD, Chief Medical Editor, Harvard Health Publishing