>each of which ended up making a stronger, more dangerous opioid This is true of some early opioids like heroin, but with e.g. Oxycontin the problem wasn’t a s

>each of which ended up making a stronger, more dangerous opioid This is true of some early opioids like heroin, but with e.g. Oxycontin the problem wasn’t a stronger opioid, it's how it ended up being prescribed. Purdue's marketing led doctors to prescribe it to more people, in higher doses, and for longer. Oxycontin isn't inherently more dangerous than the dose of immediate release oxycodone or morphine that would have an equivalent effect. Innovation in opioids shouldn't just be written off. They're still the best (and sometimes the only effective) treatment for a huge number of people, and some new opioids like buprenorphine/combos like Suboxone have real advantages. The lesson from Oxycontin is more about deceptive marketing and prescribing practices.