4 ms·
[testing positive for the disease but it's not progressing] -- Yes, exactly this. There are people with two copies of the bad APOE4 gene. 95% of them develop ea
by ahazred8ta 8mo ago
[testing positive for the disease but it's not progressing] -- Yes, exactly this. There are people with two copies of the bad APOE4 gene. 95% of them develop early-onset Alzheimer's in their 50s. The medical community is now very intensely studying the remaining 5% to find out what's causing them to NOT get sick.
- RiverStone 8mo agoCan you provide the source for the 95% figure?
- ahazred8ta 8mo agoSloppy wording. -- Fortea (2024) -- Over 95% of people with two copies have amyloid beta in their cerebrospinal fluid. (not full-blown Alzheimers symptoms, just early detection) https://www.theguardian.com/society/article/2024/may/06/scientists-genetic-form-of-alzheimers-two-copies-gene-variant https://www.theguardian.com/society/article/2024/may/06/scie...