3 ms·

Myelin repair promoted by clemastine fumarate in nonhuman primate model

• bikenaga 8mo ago
  [dead]
• Yapping7880 8mo ago
  Pretty interesting. There was a study about Clemastine use as a potential treatment/prolonging for ALS, but it did not show any significant benefit at preventing/delaying neuron death. I bring it up ALS because there are certain treatments for MS (like IVIG Infusions) that can also be beneficial for ALS patients. https://pmc.ncbi.nlm.nih.gov/articles/PMC10568021/ https://pmc.ncbi.nlm.nih.gov/articles/PMC10568021/
• pogue 8mo ago
  That's super unusual, as clemastine is another first generation antihistamine that's also anticholinergic. Other anticholinergic antihistamines have been shown to lead to increased dementia effects in users. https://en.wikipedia.org/wiki/H1_antagonist https://en.wikipedia.org/wiki/H1_antagonist