4 ms·
Interesting take for me is that melatonin (over-)usage can be severely harmful for the individuals. ... over-the-counter melatonin supplements can contain an
by pvtmert 8mo ago
Interesting take for me is that melatonin (over-)usage can be severely harmful for the individuals.
... over-the-counter melatonin supplements can contain anywhere between 10 to 30 times as much melatonin as is optimal to maintain circadian hygiene. If you have ever taken melatonin and got immediately knocked out cold, had weird dreams and woke up in the middle of the night sweaty or shivering, you likely took too much—which, to be clear, is not your fault, it’s the default in the US and Canada. The mega-doses in stores serve as hypnotics (punches you to sleep), but wreck sleep architecture. The right dose is ~0.3 mg, which is hard to find in pharmacies but can be found online.
- IAmBroom 8mo ago> The right dose is ~0.3 mg, I've heard this before, but the only metastudy I could find strongly supports a dose of 3 mg 3 hours before bedtime. Dose effectiveness effectively halves when taking less than ~2 mg or more than ~10 mg. https://onlinelibrary.wiley.com/doi/10.1111/jpi.12985 https://onlinelibrary.wiley.com/doi/10.1111/jpi.12985