depends on the workload and how they've done it pure CPU should be essentially unaffected, if they're not emulating the MMU/page tables in software the differ

depends on the workload and how they've done it pure CPU should be essentially unaffected, if they're not emulating the MMU/page tables in software the difference in IO ranges from barely measurable to absolutely horrible, depending on their implementation traps/vmexits have another layer to pass through (and back)