I agree, normally in a research the size of sample should be proportional to the size of the population. The sample size of 33 doesn’t say anything while the si

I agree, normally in a research the size of sample should be proportional to the size of the population. The sample size of 33 doesn’t say anything while the size of population is a few million. Specially, when it is easy to access this population, this is not a research on a rare type of disease.