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The no control for medication is primarily based on the conclusions of Boutros 2008, a summary of spectral abnormality studies of schizophrenia. I reproduced a

The no control for medication is primarily based on the conclusions of Boutros 2008, a summary of spectral abnormality studies of schizophrenia. I reproduced a table from the paper in the appendix. What type of psych drugs were you working with? As an aside drugs used to treat schizophrenia have especially nasty side-effects, such as weight-gain, reduction of white blood cells, and--ironically--some of the "negative" symptoms of schizophrenia when given to healthy people. In fact the Soviets used to use antipsychotics to torture political prisoners. I concur that active EEG could lead to a much more accurate diagnosis, however we had access to quite a bit more resting data, and it does make the math easier (stationarity for one). Standardization of other factors would also probably increase accuracy, but once again, I was limited by my data. Since I'm no longer in academia, I won't be continuing the research, but hopefully further studies address these questions in more detail.

vacri 14y ago
Sorry, it's so long ago that I can't recall the drugs, only that as techs we had to report what was on the referral. We'd do our tech reports and the official report done by the neurologist would refer to the flat, beta-filled EEG as being 'normal for -foo-'. Part of me wants to say benzos, but I'm not sure if that's confabulation on my part. I understand the limitation of the data - it's particularly hard to get access to inpatients as subjects for new studies. Thanks again for sharing your thesis - sorry I can't converse a bit more intelligently about it at the moment. EDIT: looks like it is benzos: Some agents, particularly benzodiazepines and barbiturates, induce fast or beta (β) rhythms, and the EEG may be a useful pointer to drug intoxication when this is clinically unsuspected. from http://jnnp.bmj.com/content/76/suppl_2/ii8.full http://jnnp.bmj.com/content/76/suppl_2/ii8.full

vacri 14y ago

Sorry, it's so long ago that I can't recall the drugs, only that as techs we had to report what was on the referral. We'd do our tech reports and the official report done by the neurologist would refer to the flat, beta-filled EEG as being 'normal for -foo-'. Part of me wants to say benzos, but I'm not sure if that's confabulation on my part. I understand the limitation of the data - it's particularly hard to get access to inpatients as subjects for new studies. Thanks again for sharing your thesis - sorry I can't converse a bit more intelligently about it at the moment. EDIT: looks like it is benzos: Some agents, particularly benzodiazepines and barbiturates, induce fast or beta (β) rhythms, and the EEG may be a useful pointer to drug intoxication when this is clinically unsuspected. from http://jnnp.bmj.com/content/76/suppl_2/ii8.full http://jnnp.bmj.com/content/76/suppl_2/ii8.full